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After looking at the docs on Isla's site, one caveat here might be the audio output levels not matching normal synth signal levels. I'd suggest something like this: https://www.modulargrid.net/e/ladik-a-520-4ch-in-line-preamp Or rather, two of them, as that'll allow you to send ALL separate channels of the S2400 right into the modular's audio path. This then makes all of those play nice with the synth effects.

As for the rest, it seems to be able to deal with most any MIDI you throw at it, so using it to "translate" clocking should work, and the specs show that the clock out on the S2400 operates at the proper +5V level. So there's your lock-up!