I wonder if there is a lag, modules respond to the second sample I think, I doubt it that gates are faster.
But that doesn't matter because of latency anyway, I sync my gear by ear so that is a non-issue for me.
I own my Emu 1616m interface for over ten years, I'm not going to change that just because it has AC coupled ports of course.
I am able to run a midiclock (DC) from my AS Fusebox but I never use it because I like my way better, far more versatile.