Sequencing is very much a personal preference.
I have the 1010 Music Toolbox. I'm not currently liking where the firmware is at the moment. They're trying to take sequencing functions out of their BlackBox and use them in the Toolbox... which is breaking the ease-of-use of some functionality, especially in making live changes. I do love how flexible the outputs are as far as LFOs, CV sequences (voltages and no gates), even audio playback.
I'm really looking at the Westlicht Performer. But they aren't manufactured, only assembled by enthusiasts. The Eloquencer seems nice but overpriced in my opinion. I think I would go with a sequencer that meets your needs first, then find a way to accommodate its HP in your set-up. Having a sequencer that doesn't work for you in the first place is a waste of HP even if it fits into the planned space.
Also, having a main sequencer is great. But it's also good to have smaller sequencers around that can also lock to your main sequencer. They are great sources of modulation information for filters VCAs, switches, etc.